La Salle, Manitoba is unincorporated community located in the Rural Municipality of Macdonald along the banks of the La Salle River, abo…La Salle, Manitoba is unincorporated community located in the Rural Municipality of Macdonald along the banks of the La Salle River, about 30 kilometres south of downtown Winnipeg. As of the 2016 Canadian Census, 1,589 people make La Salle their home.
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