3D organoid models identify potential treatment targets for a devastating pediatric kidney disease by Noah Brown, Massachusetts General Hospital CDH1 + distal nephron dilates in PKHD1 −/− ...

Scientists use these systems to biochemically mimic the 3D in vivo environment on a microscale. 18 For instance, by pairing organoids and organ-on-a-chip devices, researchers have investigated how ...

Researchers have used cutting edge technology to bioprint miniature human kidneys in the lab, paving the way for new treatments for kidney failure and possibly lab-grown transplants. The study, led by ...

The team, which published its study “Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model” in Science Translational Medicine, notes that ...

These and other 3D organoid models developed by Predictive Oncology substantially complement its AI-driven 2D platform and 3D spheroids, which utilize human tumor samples to accelerate drug ...

Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in ...

3D Organoid Models Identify Potential Treatment Targets for a Devastating Pediatric Kidney Disease. Organoids—lab grown cells or tissues that resemble organs—serve as a new tool for disease ...

MCRI Professor Melissa Little, a world leader in modelling the human kidney, first began growing kidney organoids in 2015. But this new bio-printing method is faster, more reliable and allows the ...