"With adaptive optics two-photon endomicroscopy, we can now study the structures and functions of the deep brain at an unprecedented resolution, which will greatly accelerate our progress in ...

The impact of two-photon microscopy on functional imaging of neuron activity was recognized when the technique's pioneers were awarded the €1 million Brain Prize in 2015, but certain practical ...

In a recent breakthrough, a team of HKUST scientists developed an adaptive optics two-photon excitation fluorescence microscopy using direct wavefront sensing for high-resolution in vivo ...

With the new Keck grant, the researchers will modify their current AO confocal microscope into a two-photon AO microscopy system. “Our two main goals are to develop the fluorescent protein guide stars ...

Adaptive optics (AO) is important to improve the imaging quality and boost microscope performance to the next level. However, ... In the paper, a two-photon, ...

Normally a conventional two-photon microscope cannot resolve the delicate structure of the dendrite spine without removing the brain tissue from the skull entirely. This is a highly significant ...

With adaptive optics, we can sort of reverse that process and cancel out these optical aberrations, retaining a really sharp image of the brain. With this sharper focus, you are not only getting ...

An adaptive optics two-photon microscopy image of layer 4 of the primary somatosensory cortex. A composite image showing the barrel structure of the primary somatosensory cortex in mice delineated ...

PARIS – Imagine Optic, French manufacturer of wavefront metrology and adaptive optics technology, has been entrusted with the leadership of MICADO (MICroscopy with ADaptive Optics), a three-year ...

The Very Large Telescope (VLT) in the Atacama Desert of Chile, operated by the European Southern Observatory (ESO), has been steadily improving its adaptive optics for almost two years. The ...