Androgen insensitivity syndrome (AIS) mostly affects males. It is known to be caused by mutations, or errors, in a gene for the androgen receptor. This gene is located on the X chromosome, which is ...

We describe a patient in whom the complete androgen-insensitivity syndrome was diagnosed on the basis of phenotypic and endocrinologic findings, but who had no mutations in the androgen receptor ...

Jackie Blankenship grew up thinking she had to hide who she is and lied about it for so long, but now she's finally embracing her reality and educating others.

In individuals affected with androgen insensitivity syndrome, also known as "testicular feminization," the first three steps occur normally— individuals inherit an X and a Y chromosome, the SRY gene ...

The researchers became aware of the previously unknown connection between actin and steroid hormones while studying the cells of patients with a so-called androgen insensitivity syndrome (AIS).

Journal Reference: Nicolás Mendoza, Miguel Angel Motos. Androgen insensitivity syndrome. Gynecological Endocrinology, 2013; 29 (1): 1 DOI: 10.3109/09513590.2012.705378 ...

Women with complete androgen insensitivity syndrome randomly assigned to receive daily testosterone therapy for 6 months experienced a marked increase in sexual desire vs. women assigned daily ...

Androgen insensitivity syndrome (AIS) is an X-linked genetic disorder of male sexual differentiation caused by mutations in the androgen receptor (AR) gene. A reliable genotype–phenotype ...