The strength of the antibody-antigen interaction is determined by two key factors: affinity and avidity. Affinity refers to the strength of the binding between a single antibody binding site (paratope ...

A team of Northwestern University scientists spanning disciplines have developed new technology that could lead to the ...

The low-cost test developed by Professor Vinayak Dravid and research professor Gajendra Shekhawat builds on an existing ...

Antibody responses by B cells become more specific over time in a process known as 'affinity maturation', but the role of antibody affinity for antigens in controlling B lymphocyte selection remains ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance ... the chance they'll acquire mutations that enhance their affinity for an antigen. As a ...

In the landmark Amgen v. Sanofi case (previously covered here), the Supreme Court affirmed that patent claims drawn to a genus of ...

H3, a key cancer antigen and immune checkpointHighly expressed on the cell surfaces of both tumor and immune cells, B7-H3 is a promising anti-cancer ...

Antibody sequences Remaining antigens Top three humanized antibodies, 0.2~0.5 mg per strain (at least one humanized ab has an equivalent affinity with parental ab) CoA H and L chains in separate ...

Technology can improve on existing platforms’ sensitivity and speed by 20 times Microcantilevers coated in specific antibodies exhibited very high affinity for corresponding HIV antigens ...