The strength of the antibody-antigen interaction is determined by two key factors: affinity and avidity. Affinity refers to the strength of the binding between a single antibody binding site (paratope ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

The smaller antibody formats such as single-chain fragment variables, nanobodies or other scaffolds that can reach hidden targets or act as intrabodies to target intracellular antigens must strike a ...

"It is a very powerful tool that depends on three basic things: sensitivity, antigen-antibody affinity and specificity. This is where HIV comes in, because HIV is so pernicious that it mutates so ...

For the druggability of antibodies to be evaluated, it is essential to guarantee their particular affinity to their antigens. This needs the choosing of the correct antigen for the antibody ...

Antibody sequences Remaining antigens Top three humanized antibodies, 0.2~0.5 mg per strain (at least one humanized ab has an equivalent affinity with parental ab) CoA H and L chains in separate ...

Technology can improve on existing platforms’ sensitivity and speed by 20 times Microcantilevers coated in specific antibodies exhibited very high affinity for corresponding HIV antigens ...