Scientists at EPFL and AstraZeneca have developed a method to map the atomic-level structure of amorphous drugs, demonstrated on a GLP-1 receptor agonist candidate for diabetes and obesity treatment.

Since the atomic structure of the material is well-known, it provided a good basis for interpreting the research group's 3D atomic-resolved ... The mathematical model makes it possible to identify ...

The whole structure was immersed in water, as many 3D biomolecular systems of interest occur in liquid environments. Fukuma and colleagues then performed 3D-AFM experiments in two different modes.

The technology succeeds in making visible information on the atomic-scale 3D structure of amorphous carbon, based on measured X-ray scattering data. By making available detailed information on the ...

Atomic AI is doing both simultaneously. A rotating 3D model of an RNA strand structure predicted by PARSE. The core of Atomic’s IP is, though this is something of a simplification, an AlphaFold ...

In the course of current therapy development, however, it would be tremendously useful to know how exactly they operate and what their 3D structure looks like at atomic detail. "Phages are ...