An expert discusses the evolving management of relapsed/refractory (R/R) large B-cell lymphoma (LBCL), illustrating how CAR T ...

Enzymes, such as γ-secretase, are able to cleave and release the extracellular domain of BCMA into the bloodstream as soluble ...

An expert discusses that this case of a 60-year-old man with primary refractory diffuse large B-cell lymphoma highlights the ...

B-ALL is an aggressive type of leukemia that affects B lymphocytes, a kind of white blood cell that originates in the bone marrow.- In this condition, B lymphocytes turn cancerous, multiplying ...

MGH study shows B cell therapy may ease ARDS by reducing lung damage, improving oxygenation, and restoring immune balance in preclinical models.

The study found that in the absence of B cells, CD8 T cells become overly active too early, burning out quickly and failing to develop into memory cells that provide long-term protection. This ...

However, in B-ALL, the body produces an overabundance of these cells that build up in our bone marrow and stop healthy blood cells from developing. They can also spread to other parts of the body.

Researchers describe six subsets of memory B cells — including one subset that produces the transcription factor T-bet. Using ...

Single B-cell technologies have emerged as powerful screening tools to accelerate antibody discovery, offering R&D teams the potential to interrogate millions of individual antibody-secreting ...

DESTIN, Fla. — An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according to a speaker at the Congress of Clinical Rheumatology ...

B cells found to be crucial for long-term vaccine protection, new study shows The new findings could help improve vaccine effectiveness in some immunocompromised patients Date: April 23, 2025 ...