Structured sequences emerge from random pool when replicated by templated ligation. Proceedings of the National Academy of Sciences , 2021; 118 (8): e2018830118 DOI: 10.1073/pnas.2018830118 Cite ...

By using Janus PNAs to bind to the hairpin’s characteristic repeating three-base sequence, Ly’s group hopes to prevent the hairpin from binding to and trapping proteins, an interaction that is ...

The recognition of specific DNA sequences by proteins is thought to depend on two types of mechanism: one that involves the formation of hydrogen bonds with specific bases, primarily in the major ...

In order to read the sequence, you must begin at the bottom of the gel with the smaller fragments and work your way up. In order to identify each base, the band patterns must be interpreted in ...

Gene expression takes place in two stages. First, in transcription, an enzyme constructs messenger RNA (mRNA), which is a strand of RNA with a copy of the base sequence of one strand in the DNA helix.

Depurination of DNA and RNA sequences is an alteration of the sugar-phosphate backbone in which hydrolysis of a purine base (adenine or guanine) occurs. Synthetic oligonucleotides suffer from such ...

Of course, not every HIV provirus has these 34-base sequences—but most of the ones infecting humans do. The sequence, found in most HIV-1 subtypes, is estimated to occur in 82 percent of ...

VideoDisruptive sequencing technique with expandable nucleotides leads to $15,000,000 financing Seattle–based, Stratos Genomics Inc, an innovator in molecular engineering and gene sequencing ...