That's where insulin normally comes from, and in type 2 diabetes there is always some insulin coming out from those beta cells; in type 1 diabetes, you tend to lose the beta cells and make no insulin.

Beta cells communicate with each other to secrete insulin in a coordinated manner. ... Germany, the Paul Langerhans Institute Dresden (PLID), and the Universities of Oulu, ...

To investigate the mechanisms of beta cell loss in T2D, researchers at the DZD performed single-cell RNA sequencing of islets of Langerhans in two obese mouse strains that differ in their ...

Dysfunctions of the tiny cell processes (primary cilia*) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An ...

In 2012, Sarah Tersey, PhD, Research Associate Professor at UChicago and co-senior author of the new study, led a project that was among the first to suggest that the beta cell might be a central ...

It was accepted that beta cells could only function correctly in the presence of the other hormone-producing cells—alpha, delta and gamma cells—grouped together in islets within the pancreas.

When Beta Cells Fail. In type 2 diabetes, which is typically associated with obesity, the body’s tissues become resistant to insulin, which means they can’t take in and use blood sugar.

Biomea Fusion, Inc. announced positive results from preclinical experiments showing that its investigational drug icovamenib enhances beta cell function and improves the responsiveness of human ...

If beta cells die prematurely, the endocrine cells normally responsible for producing other hormones, such as glucagon or somatostatin, can start producing insulin.

The bodyguards zero in on beta cells because they recognize a specific protein, called CD19, that the researchers added to the beta cells. When the bodyguard cells grab onto CD19, they then crank ...