This observation helps to differentiate this type of abnormality from the bicarbonate loss in gradient type RTA, in which a small constant rate of excretion of bicarbonate in urine persists ...

[Hales] has been on a mission for a while to make his own diodes and put them to use and now he’s succeeded with diodes made of sodium bicarbonate and water, aluminum tape and soldered copper.

Over a decade ago, a group from the Section of Dialysis and Extracorporeal Therapy at The Cleveland Clinic, OH, developed a bicarbonate-based dialysate for use during continuous renal replacement.