Artificial biosynthetic pathways are typically assembled and optimized progressively, from earlier to later steps. This commentary highlights the potential of an alternate regressive method for ...

A new study demonstrates how plants of the nightshade family produce pharmaceutically valuable compounds and how this biosynthesis is epigenetically regulated. Plants are masters at producing a ...

Anabolic – this type of pathway requires energy and is used to build up large molecules from smaller ones (biosynthesis). Catabolic – this type of pathway releases energy and is used to break ...

In addition, the researchers designed two auxotrophic yeast strains (met15Δ and ade2Δ) to form a mutualistic relationship, cross-feeding metabolites while dividing the biosynthetic pathway into ...