Find out what you need to know about the CD4:CD8 ratio test. Learn why your doctor asks for it, what information they get from it, and what it means for you.

Immutep Limited (ASX: IMM; NASDAQ: IMMP) (“Immutep” or “the Company”), a late-stage immunotherapy company targeting cancer ...

CD4+ T cells can trigger and coordinate the immune response. They recognize pathogens and secrete cytokines that activate other immune cells, including CD8+ T cells.

Secondary/exploratory objectives include cellular kinetics of TCR T cells, T cell phenotype, tumor infiltration kinetics, and MHC-I expression dynamics over time. After the first 12 months, patients ...

The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been ...

In autoimmune diseases, CD4+ T cells targeted to self- antigens multiply and attack the body's own tissues. The resulting inflammation and cell damage leads to disease such as diabetes, rheumatoid ...

Several lines of evidence support that CD8+ T cells trigger microglial activation: (1) In CD8+ T cell depletion, MHC-II+ IFN+ microglia are diminished, whereas in microglia depletion, CD8+ T cells ...

Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-26045-w ...

They found that immune system cells called CD8 T lymphocytes predominate in inflamed heart tissue of mice afflicted with myocarditis. These same activated T cells are necessary to trigger myocarditis ...