Heart inflammation, or myocarditis ... post SARS-CoV-2 infection, CD8 T cells tended to be more dominant. In the non-COVID-19 myocarditis samples, the CD4 to CD8 cell ratio was about 50/50 ...

Ischemic heart disease is a common consequence of coronary artery disease (CAD), which is primarily driven by atherosclerosis, a chronic inflammatory ...

Letermovir, an antiviral drug for cytomegalovirus (CMV), was associated with reduced inflammation, improved CD4/CD8 T-cell ratios and better physical ... in the long term to many conditions such as ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic potential. Atherosclerosis is the most common cause of life-threatening ...

One type of T cell—known as a CD8—is constantly on the prowl in the human body in search of intruders that can cause infections and disease. CD8 T cells transform, or differentiate ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

CD8 + T cells that normally kill cancer cells often become exhausted and stop. To overcome that, some cancers, such as TNBC, can be treated with immune checkpoint inhibitors, which inhibit ...