NETO2 is suggested as a potential therapeutic target for melanoma, highlighting its role in facilitating melanoma progression through the CaMKII/CREB signaling pathway.

NETO2 is suggested as a potential therapeutic target for melanoma, highlighting its role in facilitating melanoma progression through the CaMKII/CREB signaling pathway.

The work entitled “Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways” was published on Asian Pacific Journal of ...

To test this pathway, the scientists targeted a CREB inhibitor to mitochondria in cultured neurons, cutting the tie between neuronal excitation and mitochondrial transcription (E-TC mito). Under these ...