Chronic cholestasis can lead to liver fibrosis and cirrhosis. The most common types of CLDs are primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC).

Biopsy also may be useful in predicting the prognosis, especially indicating the possible evolution of chronic cholestasis. Biochemical evidence of improvement after drug withdrawal is ...

The principle of therapy for chronic inflammatory liver diseases ... from any associated autoimmune diseases, particularly cholestasis and cirrhosis-related complications. For primary sclerosing ...

in addition to cholestasis, marked, diffuse fatty degeneration, which probably antedated the operation and was related to the chronic tuberculosis. In all 12 cases the course of jaundice was ...

PBC predominantly affects the epithelial cells of small bile ducts, leading to chronic intrahepatic cholestasis.

Chronic, recurrent pyogenic cholangitis promotes the formation of pigment stones and inflammatory strictures, which further aggravates cholestasis. The duration and degree of obstruction ...

A comprehensive proteomic map of liver fibrosis progression and healing in two mouse models identifies etiology-specific extracellular matrix components, laying the foundation for targeted ...