Colon cancer remains a major global health concern, ranking third among the most diagnosed cancers and leading causes of ...

In mature crypts, myosin remained stable, locking the structure in place. The researchers also found that lumen pressure acts as a long-range signal that can synchronize crypt formation across an ...

Researchers have improved upon existing organoids, creating a miniature 3D colon complete with immune cells that could lead to the development of personalized treatments for colon-related diseases ...

This study builds upon similar work published online Jan. 26, 2023 in Nature Biotechnology, which was led by Michael Helmrath, M.D., at Cincinnati Children's and co-authored by Wells and colleagues.

3D Mini Human Colons With Immune Cells Developed to Advance Treatments for Colon-Related Diseases ... a colon organoid is formed, featuring layers that mimic the natural structure of bodily tissue.