Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

They then introduced the desired cytokine molecule engineered with a compatible DBCO chemical group so that it attached to the T cell via the sugar. Having assessed the effectiveness of the attachment ...

Cytokine networks are crucial aspects of tumour immunology, particularly for colorectal cancer (CRC), in which inflammation and antitumour immunity are key determinants of disease progression.

Conventional thinking about interrogating a biological process with small molecule compounds dictates using highly specific agents to modulate the action of a single target selectively and ...

Real-time cytokine measurement. An approach to monitoring cytokines is Ella, a fully-automated, microfluidic platform that supports multiplex sandwich immunoassays.

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute ...

Notably, the addition of ruxolitinib, a small molecule inhibitor of JAK1/JAK2, to block the IL-6/JAK/STAT3 signaling pathway resulted in a significant decrease in the levels of these cytokines in ...