RNA polymerase motors down the DNA chain, reading the code of DNA "letters" as it transcribes instructions into RNA molecules, which then direct protein building.

What am I looking at? This is a 3D rendering of an RNA polymerase II enzyme from baker’s yeast, created using actual molecular data to reconstruct its shape and active sites. What looks like a ...

Greedy accumulation-directed evolution generated multi-site combinatorial mutants of T7 RNA polymerase (T7 RNAP), breaking ...

Finally, DNA polymerase extends the primers, synthesizing new DNA strands. This cycle repeats, exponentially amplifying the DNA. Key Components of PCR. PCR relies on several essential components to ...

To determine where DNA polymerase was and what it was doing, Xu and his colleagues combined two methods: confocal microscopy and optical tweezers. The team stretched an 8,000 kilobase strand of DNA ...