We designed 96 un-modified 50-mer DNA oligonucleotides, one for every 2 kb of the longest human genes known: Titin, Nebulin and Obscurin, all expressed in human muscle (Gene length ~100kb). DNA ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

DNA has to be carefully organized and packaged so it will fit into the nucleus of cells; compacted DNA that's been organized with other proteins is known as chromatin. The structure of the genome can ...

Epigenetic landscape modulates pioneer transcription factor binding Date: May 24, 2023 Source: St. Jude Children's Research Hospital Summary: Scientists studied how the epigenetic landscape ...

Study on DNA transcription uncovers links to neurodegenerative disease. Feb 27, 2023. Innovative bead design will enhance single-cell transcriptomics accuracy. Mar 13, 2025.

Transcription factors are proteins that bind to specific DNA sequences to control gene expression, guiding cells to become specific types—such as skin, muscle, or placenta cells.

New mechanism for terminating transcription of DNA into RNA in bacteria. ScienceDaily. Retrieved April 27, 2025 from www.sciencedaily.com / releases / 2021 / 05 / 210507160000.htm. Penn State.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism ...

The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription, and answer long-standing questions about the initiation mechanism and ...