The structure of the genome can influence gene expression because active genes have to be physically accessible to the cell's transcription machinery. Chromatin contains loops that can connect parts ...

Intrinsic termination relies on an RNA hairpin structure that forms in the RNA molecule being produced, ... (2021, May 7). New mechanism for terminating transcription of DNA into RNA in bacteria ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

The articles in this Subject space describe the science surrounding the structure and function of DNA. Here, you will find information on the chemical structure of DNA; organization of DNA into ...

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription, and answer long-standing questions about the initiation mechanism and ...

A team that includes Rutgers University-New Brunswick scientists has unlocked some of the secrets of corn DNA, revealing how ...

The team discovered that IPMK binds directly to SRF, altering the three-dimensional structure of the SRF protein ... Single-molecule analysis reveals that IPMK enhances the DNA-binding activity of the ...

Transcription factors are proteins that bind to specific DNA sequences to control gene expression, guiding cells to become specific types—such as skin, muscle, or placenta cells.