A new drug has shown promise in combating Parkinson’s disease while minimizing unwanted side effects.

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with ...

“That, to me, is surprising and new and exciting.” Analyzing activity of dopamine receptors also reinforced the role this neurotransmitter plays in changing stages of sexual behavior. Miyasaka ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Hypericin has also been found to have significant activity at D3 and D4 dopamine receptors. Collectively, these pharmacological effects may play a role in the efficacy of St. John's wort in the ...

For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility ... were scanned with the D 2/3 receptor ligand 18 F-fallypride in a two-part ...

Osugo et al show in healthy humans that sustained dopamine D2/D3 receptor antagonism impairs motivated behaviour, hedonic experience, and emotional expression, and that this is related to blunted ...