A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

“The end game is trying to relate [dopamine signaling] back to schizophrenia and other disorders with working memory impairment,” study coauthor Joshua Roffman of MGH and Harvard University told The ...

To this end, radioreceptor and functional studies of these three compounds were conducted at each of the known molecular isoforms of the dopamine receptors in several transfection systems ...

Levodopa — which is converted into dopamine in the brain and targets the D2/D3/D4 dopamine receptors — has been linked to side effects including sleep disorders, hallucinations, impulse ...