Glucagon-like peptide-1 (GLP-1) receptor agonists are peptide-based therapeutics for treating diabetes and for weight loss.

In vivo models provide information from ... We and others have qualified our liver MPS for applications in drug administration, to understand ADME, clearance and the bioavailability of drugs.

Tracking targeted drug delivery is often a challenge due to limitations in current imaging techniques. A recent study by ...

Jessica [email protected] Basic Medical Sciences Drug Synthesis/Optimization, In Vivo Disease Models, ADME/DMPK/Tox Diabetes, Neurological Disorders Foster, David [email protected] Department Of ...

The IDBI operates physical service cores to provide access to key drug development steps, e.g., assay development, compound screening/counter screening, target validation, ADME/PK ... testing with in ...

The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, traditional methods for screening drug candidates, such as cardiomyocyte-based ...

Predictive human organ models can be used to find therapeutic targets, understand drug ADME characteristics ... insights can be used to refine in vivo experimental design by justifying the ...

in vitro data may be extrapolated to in vivo clinical predictions. CN Bio is a close-knit team of passionate scientists, engineers and creative thinkers, all working together towards a shared goal – a ...

But while immunotherapy drugs offer new treatment possibilities ... PTPN2/N1 inhibitor with drug-likeness properties and in vivo oral absorption, supported by the Company's generative AI drug ...