Additionally, the research team tested a promising drug in combination with an existing therapy that achieved total remission in one breast cancer model that was resistant to the standard of care ...

One of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on ...

Researchers have created an AI model to design antibiotics that inhibit the growth of Acinetobacter baumannii, ... drug-resistant infections were responsible for an estimated 4.95 million deaths.

Researchers at the Francis Crick Institute have mapped the human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive. Shutting down these pathways may offer a new way ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen receptor axis have significantly delayed disease progression. However, drug ...

Researchers at the Francis Crick Institute have mapped the human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive.

In their research article summary Le Roche and colleagues concluded, “Our findings establish MED6-189 as a multitarget compound with limited capacity for the parasite to develop drug resistance ...

Cleveland Clinic researchers are working to improve the way we use evolutionary modeling to understand drug resistance. The study, published in Science Advances, uses a new type of evolutionary ...