Endomyocardial biopsy (EMB) use varies widely even among cardiovascular centers of excellence. Authors explore risks of the procedure and indications for use.

Agreement that non-invasive alternatives to EMB are not ready for routine rejection surveillance. ... with each center determining its preferred frequency of biopsy.

Prospective DEFINE-HT Study Demonstrates that Prospera™ Heart is Predictive of Clinical Outcomes and Outperforms Biopsy in Predicting Graft Dysfunction Provided by Business Wire Apr 29, 2025, 8: ...