Recently, a transcription factor called snail has been described as a potent repressor of E-cadherin expression and an inducer of epithelial-to-mesenchymal transition. 21–23 To determine whether ...

Background: Tumor cells that have undergone an epithelial-to-mesenchymal (EMT)-like phenotypic transformation in situ have been implicated in tumor cell invasiveness and disease progression.

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited treatment options. IPF is thought to result from repeated microinjuries to aging lung tissue, triggering ...

Epithelial–mesenchymal transition is reported to be implicated in many tumoral mechanisms, mainly invasion and motility, which lead to a more aggressive behavior of tumors and, consequently, to ...

Although a variety of hypotheses have been presented as to the biphasic nature of these tumors, carcinosarcomas seem to represent the best example in human cancers of the concept of ...

A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) developed a novel method for idiopathic pulmonary fibrosis (IPF ...