The transition from an epithelial to mesenchymal phenotype that occurs during EMT has been associated with metastatic progression; apical–basal polarity is lost during this process and cell ...

Epithelial-mesenchymal transition, cell polarity and stemness-associated features in malignant pleural mesothelioma. Cancer Lett 2011; 302 ; 136–43. Article CAS PubMed Google Scholar ...

Background: Tumor cells that have undergone an epithelial-to-mesenchymal (EMT)-like phenotypic transformation in situ have been implicated in tumor cell invasiveness and disease progression.

The shift from a stationary cell state with specialized functions to a more migratory cell state is called the epithelial-to-mesenchymal transition, or EMT. “When cells undergo that transition, they ...

More information: Xiaolong Zhu et al, Acetate controls endothelial-to-mesenchymal transition, Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.05.010 Journal information: Cell Metabolism ...