Across many cancers, mortality is associated with metastasis and acquired drug resistance, both of which often manifest in recurrent disease. Central to these phenomena is epithelial to mesenchymal ...

623 Background: The detection of ≥ 5 CTCs by CellSearch in women with metastatic breast cancer (MBC) is predictive of early recurrence and poor survival. ... Epithelial-mesenchymal transition in ...

PURPOSEThe presence of epithelial-mesenchymal transition (EMT) in breast cancer (BC) cells has been linked to worse prognosis and may influence response to systemic treatment. ... 32 de novo ...

Sep. 2, 2020 — Scientists studied how cancer cells are able to divide in a crowded tumor tissue and connected it to the hallmark of cancer progression and metastasis, the epithelial-mesenchymal ...

This new article publication from Acta Pharmaceutica Sinica B , discusses how a psychological stress-activated NR3C1/NUPR1 ...

Towards elucidating the connection between epithelial-mesenchymal transitions and stemness. Journal of The Royal Society Interface , 2014; 11 (101): 20140962 DOI: 10.1098/rsif.2014.0962 Cite This ...

Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown mechanism that affects the ability of cancer cells to spread in the body. The ...

Under the microscope, MSK scientists studied how cells in a mouse embryo (green) move out and break away from their original tissue by contracting their surfaces (red). Studying this process, known as ...

During embryonic development, the process of epithelial-mesenchymal transition (EMT) allows the migration of cells to different destinations to form organs and tissues. This same program is used ...

Different mechanisms have been proposed to account for tumor heterogeneity such as epithelial to mesenchymal transition (EMT), a process in which epithelial tumor cells loose their adhesion and ...