In their GTP-bound form, they interact with a diverse range of different targets to induce cellular responses. In addition to GTP–GDP cycling, Rho GTPases are regulated by a diverse range of ...

The ADP-ribosylation factor (ARF) and ARF-like (ARL) family of G proteins, which are known to regulate membrane traffic and organelle structure, are emerging as regulators of diverse processes ...

Ner findings show how a specific nucleotide metabolite called GTP controls responses to radiation and chemotherapy in an unexpected way. Metabolites called nucleotides are the building blocks of ...