Derided by some as "junk DNA" with no clear function, roughly 151 million base pairs of sequence data scattered throughout the genome were still a black box. "You would think that, with 92 percent ...

which made it challenging to string the DNA together in the correct order using previous sequencing methods. The researchers relied on two DNA sequencing technologies that emerged over the past ...

Our findings confirm that i-motifs are not just laboratory curiosities but widespread—and likely to play key roles in genomic function." Animation of DNA's knot-like i-motif structure the team ...

Researchers unveil the fractal globule structure of DNA, providing new insights into genome organization and its implications ...

So how, then, do researchers determine the sequence of A's, G's, C's, and T's that comprise the genome? The answer is that they've had to develop a new process, what Bruce Birren of MIT's ...

Researchers utilized recently published telomere-to-telomere genomes of humans, chimpanzees, bonobos, gorillas, and two orangutans to predict where DNA sequences might form alternative structures ...

In addition, a greater understanding of the relative proportion of thyroid function explained by common variants is now possible with the availability of whole-genome sequencing (WGS) and this is ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor ...

New technology has made identifying the function and targets of regulatory sequences much easier. Scientists can now manipulate cells to obtain more information about their DNA, and, thanks to ...

Increasing evidence suggests these noncoding sequences might help cancer defeat treatment, and experts now see them as promising tools for cancer diagnosis. Despite the number of functions now ...