Alpha-2 Adrenergic Agonists. Medications like clonidine and guanfacine are often used for kids with mild to moderate tics—especially when ADHD is also present.

The drug contains guanfacine, a selective alpha-2A adrenergic receptor agonist. ... EMA Endorses Two ADHD Treatments for Children - Medscape - December 13, 2024. Comments .