The hedgehog (Hh) signaling pathway regulates the differentiation and growth of numerous cell types, including chondrocytes, and thus is essential for normal skeletal development. Pharmacological ...
pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement ...
New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...
News Medical on MSN1mon
Study uncovers pathway behind age-related degeneration of eye glandsThe researchers identified markers for stem cell populations that maintain distinct regions of the meibomian glands, and ...
1monon MSN
The researchers identified markers for stem cell populations that maintain distinct regions of the meibomian glands, and ...
Yet it still remains unknown how a signaling pathway can be differentially modulated to yield unique outcomes from similar cellular contexts. Recently, it has become clear that glycosylation as well ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
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