Interleukin-2 (IL-2) is a cytokine that is critical to the regulation of T-cell responses. IL-2 also has a huge range of immunostimulatory and immunomodulatory functions.

These in vivo differences suggest that, although IL-15 and IL-2 exert some common in vivo functions, they also have key distinct functions, as illustrated by the following observations.

Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Lightfoot, Colin. (2021, October 07). Critical function of IL-7 in diagnosis, prognosis, and ...

ALZHEIMER’S disease (AD), a neurodegenerative condition marked by cognitive decline and progressive memory loss, has long been associated with chronic inflammation and immune dysregulation. Regulatory ...

Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection. Science Immunology, 2022; 7 (68) DOI: 10.1126/sciimmunol.abl6322; ...

XmAb564 is engineered with reduced binding affinity for IL-2's beta receptor (IL-2Rβ, CD122) and increased binding affinity for its alpha receptor (IL-2Rα, CD25).