BUFFALO, N.Y. -- The promise of new pharmaceutical treatments from a class of powerful plant compounds called isoflavonoids has remained unfulfilled because of problems biosynthesizing sufficient ...

In isoflavonoids, the number and positions of the hydroxyl substituents determine the degree of steric homology with 17β-estradiol and therefore the binding affinity for the estrogen receptor.

Morris PF, Savard ME, Ward EWB (1991) Identification and accu- mulation of isoflavonoids and isoflavone glucosides in soybean leaves and hypocotyls in resistance responses to Phytophthora megasperma f ...

"This is an important, initial step in the construction of a system that can potentially synthesize thousands of natural and non-natural isoflavonoids," says Mattheos A. G. Koffas, PhD, associate ...