MEK-ERK signaling is required for S phase entry and controls levels of cyclin D1 and p27 Kip1 in NHEM. Serum-starved NHEM were detached with trypsin and pelleted in MCDB 153 medium containing 1 mg ...

MicroRNAs (miRNAs) are increasingly implicated in regulating tumor malignance through their capacity to coordinately repress expression of tumor-related genes. Here, we show that overexpression of ...

Incidence of syn- and metachronous adrenal metastasis following tumor nephrectomy: A retrospective bicenter analysis. Background: p27Kip1 is considered to contribute to the progression of ccRCC and is ...

Background: The assessment of the cyclin-dependent kinase inhibitor p27/Kip1 & the cell proliferation marker Ki67/MIB1 immunohistochemical (IHC) expression (E) as predictive indicators of prostate ...