MicroRNAs (miRNAs) are increasingly implicated in regulating tumor malignance through their capacity to coordinately repress expression of tumor-related genes. Here, we show that overexpression of ...

Downregulation of p27 (cyclin-dependent kinase inhibitor-1B, CDKN1B or KIP1) is caused by increased ubiquitin-mediated proteasomal degradation in colorectal cancer, and has been associated with ...

Background: The assessment of the cyclin-dependent kinase inhibitor p27/Kip1 & the cell proliferation marker Ki67/MIB1 immunohistochemical (IHC) expression (E) as predictive indicators of prostate ...