Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like ...

The method, which makes use of off-the-shelf light microscopes, hydrogel and deep learning, was published in Nature. Advanced Search. ... The brain tissue of interest is embedded in this hydrogel.

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain ...

Microscope system sharpens scientists' view of neural circuit connections Date: June 4, 2024 ... works by scanning brain tissue with lines of light in perpendicular directions.

As an alternative, MIT researchers have developed a single-step technique for expanding tissue before imaging it, making it possible achieve nanoscale resolution with a conventional light microscope.

Researchers previously relied on costly, super-high-resolution microscopes to image nanoscale structures in cells and brain tissue, and, even with the most advanced technology, they often ...

This microscope photo provided by the McLean Hospital's Harvard Brain Tissue Resource Center in January 2024 shows cells in the caudate nucleus structure of the brain in a person with Huntington's ...

This microscope photo provided by the McLean Hospital's Harvard Brain Tissue Resource Center in January 2024 shows cells in the caudate nucleus structure of the brain in a person with Huntington's ...

"We present an ExM protocol that achieves 20× expansion, yielding . 20-nanometer resolution on a conventional microscope, in a single expansion step." At the 20-nanometer resolution achieved by this ...

This microscope photo provided by the McLean Hospital’s Harvard Brain Tissue Resource Center in January 2024 shows cells in the caudate nucleus structure of the brain in a person with Huntington ...