The fact that elevated plasma levels of homocysteine are associated with vascular disease and thrombosis is now in little doubt, but the nature of this relationship remains unclear. Does high ...

Vitamin supplements could counter homocysteine’s effect on collagen, since both folate and vitamin B12 lower homocysteine concentrations in the blood, says Sally P. Stabler of the University of ...

People with high blood levels of the amino acid are at increased risk for heart disease and strokes. A new study shows that reducing the level of homocysteine does not cut those risks.

Patients with end-stage kidney disease treated with high doses of folic acid and B vitamins to lower homocysteine levels did not have improvement in survival or reductions in the incidence of ...

What should be done about an elevated homocysteine level that persists despite administration of high-dose folic acid and high ... Treatment With Folate to Lower Homocysteine . Erica Brownfield, MD.

Folic acid doses as low as 0.2 mg/day given for 6 months can effectively lower homocysteine concentrations, and higher doses result in no further significant lowering.

As expected, homocysteine levels at follow-up were significantly lower in patients assigned to folate treatment than in those assigned to placebo (7.2±2.4 vs. 9.5±3.6 μmol per liter, P<0.001 ...