Leukemia - Lymphocyte subpopulation imbalances, ... which is characterized by BM dyshematopoiesis and/or maturation arrest of the granulocytic series mimicking primary MDS.

A study by the Josep Carreras Leukaemia Research Institute reveals a mechanism that controls B-lymphocyte maturation, with SIRT7 playing a critical role. This insight could lead to new treatments for ...

Antibodies on the surface of B lymphocytes trigger adaptive immune responses and control a series of antigen-independent checkpoints during B cell development. These physiologic processes are ...

Ex-vivo culture with γchain cytokines restores defective maturation and activation of tumor infiltrating lymphocytes in indolent non-Hodgkin’s lymphoma M. A. Di Nicola , C. Carlo-Stella , R. Mortarini ...