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The M13 phage’s special abilities involved a set of proteins displayed on the tip of the virus, called GP3. NPT088 uses GP3 proteins. NeuroPhage’s lead candidate, NPT088 is a differentiated drug ...
The researchers tested this opportunity with the M13 phage, a filamentous virus 1000 nanometres long but only 5 nanometres wide (one nanometre is one-billionth of a metre).
This in vivo experiment demonstrates the safety and effectiveness of a combined engineered M13 phage-GET-IL-12 cancer vaccine. It produced an effective anti-tumor immune response, ...
Unlike some other types of phage, M13 does not carry genes for toxins. It has a long record of being innocuous to humans, and in NeuroPhage’s hands, as well, experiments in some 300 aged transgenic ...