Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...
TAP–GFP motility was also correlated with the transport of MHC class I molecules from the ER to the plasma membrane, a result that was anticipated, as MHC class I peptides can only translocate ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...
A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.