Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...

Finally, investigators inhibited polycomb repressive complex 1 (PRC1), which works to antagonize ... More information: Te Zhang et al, An epigenetic pathway regulates MHC-II expression and ...

Some recent studies have suggested that T cells can become activated via recognition of donor MHC molecules transferred on recipient antigen-presenting cells (semidirect pathway). Activation of T ...