Prices for the 2026 Mercedes-Benz S450 range from $251,600 to $251,600. Compare prices of all Mercedes-Benz S450’s sold on CarsGuide over the last 6 months. Use our free online car valuation tool to ...

Mercedes-Benz set out to restore the S-Class' place amongst the greatest sedans in the world. In the heavily-optioned, near-$250K-plus S450 as well as the extended S450L at $300K as tested (the sweet ...