When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and ...

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy ...

In the current study, the DKFZ-led team found that a specific chemical modification process found in mitochondrial tRNA, known as mitochondrial cytosine-5 RNA methylation (m5C), drives the ...

Their study, published in The EMBO Journal, reveals the detailed mechanisms of how mitochondria process transfer RNA (tRNA) molecules, which are essential for energy production.

Recent studies have elucidated several mechanistic nuances of mitochondrial translation. In one notable investigation, ... thereby indirectly modulating the translation process [4].

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized and translated into more protein, while directing others to be degraded and ...