Pretibial myxedema, also called thyroid dermopathy or localized myxedema, is characterized by asymptomatic, cutaneous induration of the skin attributable to accumulation of acid ...

A novel approach of injecting steroids deep into the dermis with small mesotherapy needles for the treatment of pretibial myxedema (PTM) has shown efficacy with good tolerability, according to a ...

While there are reports of local trauma clearly contributing to the pathogenesis of pretibial myxedema, direct evidence for a similar mechanism in Graves' ophthalmopathy (GO) has been lacking.