Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

Large-scale redesigns, including changes to core domains, may retain stability—challenging assumptions that such regions are off-limits.

As most therapeutic protein formulations are challenging and costly to produce with high yields, biopharmaceutical firms require instruments that deliver quick, excellent protein stability data ...

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In a study published in the journal Nature, researchers from the Center for Genomic Regulation (CRG) and the Wellcome Sanger Institute have discovered that mutations affect protein stability ...

The research team used AlphaFold2 to explore how mutations affect protein stability - a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's.

Protein mutant stability can be inferred from AI-predicted structures AlphaFold2 predicts structural effects of mutations that are correlated with changes in stability ...

Protein Mutant Stability Can Be Inferred from AI-Predicted Structures Aug. 28, 2024 — Researchers have taken a significant step forward in understanding the stability of proteins by leveraging ...

Appreciate the relevance of all aspects of protein stability as a key factor in selecting candidates/formulations in developability; Learn how Aunty assesses thermal, colloidal, and long-term ...