At higher magnification these foamy macrophages were easily apparent in the pulmonary airspaces (arrowhead) and in the alveolar walls (arrows) of the ASMKO lungs compared with normal mice .

More information: Huachun Cui et al, TREM2 promotes lung fibrosis via controlling alveolar macrophage survival and pro-fibrotic activity, Nature Communications (2025). DOI: 10.1038/s41467-025-57024-0 ...

Looking specifically at alveolar macrophage cells under a microscope, the researchers measured the sizes of the cells and the amount of carbon accumulated in the cells. They found that the average ...

Levels of macrophage colony-stimulating factor (M-CSF), which has regulatory effects on myeloid cells that overlap with the regulatory effects of GM-CSF, are increased in patients with pulmonary ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

James Baker, Sophie Booth, Josiah Dungwa, Andrew Higham, Dave Singh, Simon Lea. Alveolar macrophage carbon is associated with COPD severity. ERJ Open Research , 2025; 00933-2024 DOI: 10.1183 ...

To the Editor: Vassallo et al. (June 29 issue)1 depict a central role for the alveolar macrophage in the pathogenesis of pulmonary Langerhans'-cell histiocytosis. We made several observations in a ...

The study found that COPD patients’ alveolar macrophages — a type of lung cell that removes dust, particles and microorganisms from the lungs — contain more carbon than those of smokers. The ...

TREM2, a cell surface receptor on monocyte-derived alveolar macrophages (Mo-AMs), is highly expressed in fibrotic lungs and promotes macrophage survival and lung fibrosis by delaying apoptosis.