A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

But Storici's team found that RNA can also help cells repair a severe form of DNA damage called a double-strand break ... beyond its traditional coding function, showing the cellular machinery ...

This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on the DNA and initiates the synthesis of the complementary RNA strand. The resulting ... of the ...

Various non-coding RNAs also play important roles in regulating gene ... the enzyme RNA polymerase uses one strand of the DNA as a template to synthesize a complementary RNA strand. The resulting RNA ...

this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA precursors and links the coding sections (exons) to form a continuous strand ...

The enzyme RNA polymerase attaches to the DNA in a non-coding region just before the gene. RNA polymerase moves along the DNA strand. Free RNA nucleotides form hydrogen bonds with the exposed DNA ...

The immune system responds to an infection by producing antibodies that recognize and bind to the cell surface of the pathogen, thus marking it as an intruder and triggering an immune response. For ...

Circular RNA is a relatively newly discovered class of such structures that form a circle rather than a strand. It regulates ... and then produce novel, non-coding, circular RNAs,” Brown told ...