Greedy accumulation-directed evolution generated multi-site combinatorial mutants of T7 RNA polymerase (T7 RNAP), breaking ...

Researchers conducted a retrospective study published in July 2025 issue of Journal of Hematology & Oncology to examine the ...

A new drug was shown to significantly reduce tumor growth in lab studies by up to 77% for melanoma and colorectal cancers.

Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies. Source: Johns Hopkins Medicine.

Colon cancer remains a major global health concern, ranking third among the most diagnosed cancers and leading causes of ...

What am I looking at? This is a 3D rendering of an RNA polymerase II enzyme from baker’s yeast, created using actual molecular data to reconstruct its shape and active sites. What looks like a ...

A significant percentage of patients with SSc first present with non-RP symptoms — most commonly puffy fingers/hands — and are associated with more severe disease.

In addition to its newly launched CleanScribe RNA Polymerase, TriLink offers mRNA capping analogs (including the award-winning CleanCap® M6), mRNA raw materials (nucleotides and other IVT enzymes ...

DNA polymerase was isolated in 1956; RNA polymerase, in 1959. Wave Life Sciences, a clinical-stage RNA medicines company, develops A-to-I RNA base editing oligonucleotides (“AIMers”).

Instead, hepatitis D virus hijacks the cellular DNA-dependent RNA polymerase II (Pol-II), normally used to produce messenger RNAs from genomic DNA.